Anticoagulants after Myocardial Infarction

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Use of anticoagulants in acute myocardial infarction.

T HE SCIENTIFIC BASIS for the use of anticoagulants in the treatment of acute myocardial infarction was established by Solandt, Nassim, and Best' in 1939. They produced mural thrombi in the hearts of dogs by injecting sodium ricinoleate into the myocardium after tying off a branch of the left coronary artery. Thrombus formation could be prevented by the injection of heparin intravenously. The a...

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The impact of an acute coronary syndrome (ACS) event, such as an acute myocardial infarction (MI), is not limited to the acute management phase; patients face an elevated risk of residual atherothrombotic events that commonly requires chronic management for months or even years. Significant advances have been made in both the acute and chronic management of patients with acute MI over the past ...

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ژورنال

عنوان ژورنال: BMJ

سال: 1969

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5650.188-b